We are pleased to announce that our latest clinical collaboration has been published in Reproductive Sciences (Springer).
The study, titled “Smartphone-Assisted CSCTAS-Derived Sperm Kinematics and Clinical Pregnancy after Intrauterine Insemination in a Turkish Cohort of Couples with Unexplained Infertility,” uses our microscope-mounted, smartphone-assisted Computerized Sperm Counting and Tracking Analysis System (CSCTAS) to characterize sperm kinematics in 184 first IUI cycles (2018–2019) and compares them by ultrasound-confirmed clinical pregnancy.
Clinical pregnancy occurred in 29 cycles (15.8%). Wobble (WOB) was higher and beat-cross frequency (BCF) lower in pregnancy-positive cycles, but effect sizes were small and single-variable AUCs (0.526 and 0.555) were near chance; Bland–Altman analysis showed a −3.44 point bias between manual and CSCTAS motility. The authors therefore present these as exploratory, population-level digital motility signals rather than standalone predictors of individual IUI outcome.
Authors:
Esra Selvi (Istanbul University, Istanbul Faculty of Medicine)
Ayşe Altun Akpınar (Istanbul University, Istanbul Faculty of Medicine)
Yeşim Erkan (Istanbul University, Istanbul Faculty of Medicine)
Hamza Osman İlhan (Yıldız Technical University)
Nizamettin Aydın (Istanbul Technical University)
Özlem Dural (Istanbul University, Istanbul Faculty of Medicine)
Necip Erkut Attar (Istanbul University / Yeditepe University)
