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New Publication in Diagnostics: A Multi-Teacher Knowledge Distillation Framework for Enhancing the Robustness of Automated Sperm Morphology Assessment

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  • New Publication in Diagnostics: A Multi-Teacher Knowledge Distillation Framework for Enhancing the Robustness of Automated Sperm Morphology Assessment

We are pleased to announce that our latest research has been published in Diagnostics (MDPI, Open Access).
The study, titled “A Multi-Teacher Knowledge Distillation Framework for Enhancing the Robustness of Automated Sperm Morphology Assessment,” proposes knowledge distillation as a strong regularizer for sperm morphology classification on small, heavily imbalanced clinical datasets. Soft distillation transfers knowledge from high-capacity teachers (SwinV2-large, EfficientNetV2-m, ConvNeXtV2-large) to a smaller SwinV2-base student, comparing single-teacher and multi-teacher (averaged-response) strategies.

Using a cross-dataset protocol on the 18-class Hi-LabSpermMorpho dataset — teachers fine-tuned on two staining sets (BesLab, Histoplus, GBL) and the student trained on the third — the multi-teacher student with augmentation and soft distillation reached 70.94% (BesLab), 73.61% (Histoplus) and 71.63% (GBL) accuracy, consistently above the baselines, offering a more generalizable solution for clinical sperm morphology assessment.

Authors:
Osman Emre Tutay (Yıldız Technical University)
Hamza Osman İlhan (Yıldız Technical University)
Hakkı Uzun (Recep Tayyip Erdoğan University)
Merve Hüner Yiğit (Recep Tayyip Erdoğan University)
Görkem Serbes (Yıldız Technical University)

Tutay, O.E., Ilhan, H.O., Uzun, H., Huner Yigit, M., & Serbes, G. (2026). A Multi-Teacher Knowledge Distillation Framework for Enhancing the Robustness of Automated Sperm Morphology Assessment. Diagnostics, 16(8), 1230.
DOI: 10.3390/diagnostics16081230

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